Health Condition 1: R688- Other general symptoms and signs Health Condition 2: null- White spot lesion following fixed Orthodontic treatment
Conditions
Interventions
Intervention1: Intervention 10% Casein Phospho Peptide -Amorphus Calcium Phosphate: Dose -
10% w/v Casein Phospho Peptide -Amorphus Calcium Phosphate.
Duration of therapy -
Patients will be instruc
Sponsors
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: Healthy adolescents between the age group of 12 to 18 years, with at least one year of remaining fixed orthodontic therapy.
Exclusion criteria
Exclusion criteria: Milk protein allergy, Chronic use of medication causing dry mouth, and Any illness/condition that the investigator deemed could affect the study outcome. Informed consent from all participants/ parents will be obtained.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the efficacy of casein phospho peptide and amorphous calcium phosphate (CPP-ACP) in the prevention of white spot lesions following fixed orthodontic therapy.Timepoint: Patients will be followed up at 2, 4, 6, 8, 10 and 12 months when they would be expected to complete their orthodontic treatment and for one month after that. | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the progression of dental caries with and without intervention using CPP-ACP in patients undergoing fixed orthodontic therapy. To study the progression of carcinogenic risk factors with and without intervention using CPP-ACP in patients undergoing fixed orthodontic therapy. Timepoint: Patients will be followed up at 2, 4, 6, 8, 10 and 12 months | — |
Countries
India
Contacts
Public ContactJogikalmat Krithikadatta
Chennai Dental Research Foundation
Outcome results
None listed