Role of repetitive transcranial magnetic stimulation (rTMS) in migraine prophylaxis a randomized control trial

A randomized placebo controlled trial evaluating the safety and efficacy of rTMS in migraine prophylaxis

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2012/04/002545

Enrollment

100

Registered

2012-04-04

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients of Migraine headache of more than 15 years age. No history of focal neurological deficit, no associated comorbidities like uncontrol hypertension, renal failure, pregnancy, lactation

Interventions

Intervention1: Repetitive transcranial magnetic stimulation: Patients left prefrontal cortex will be stimulated by repetitive transcranial magnetic coil(Magstim Rapid, Whitland, Wales, UK). Each sessi

Eligibility

Inclusion criteria

Inclusion criteria: Patients of migraine headache with frequency of attacks more than four attcaks per month.

Exclusion criteria

Exclusion criteria: Pregnancy, liver or kidney diseases, malignancy, severe hypertension, pacemaker or metallic implants and history of seizure or structural brain lesions

Design outcomes

Primary

Measure	Time frame
1. More than 50% improvement in frequency of headache 2. Global improvement in VASTimepoint: 1 month	—

Secondary

Measure	Time frame
Severity of headache, Functional improvement, rescue analgesic intake and somatosensory evoked potential before and after rTMS in selected patientsTimepoint: 1 month	—

Countries

India

Contacts

Public ContactDr U K Misra

SGPGIMS

drukmisra@rediffmail.com0522-2494167

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026