Health Condition 1: null- Recurrent Epithelial Ovarian Cancer
Conditions
Interventions
Intervention1: metformin: Dose - 500 mg twice daily orally
for one year
Control Intervention1: placebo(starch powder): Dose - 500 mg twice daily orally for one year
Sponsors
Dr Reddys Laboratories Ltd
Eligibility
Inclusion criteria
Inclusion criteria: Patients of recurrent epithelial ovarian cancer Age more than 18 years and up to 70 years
Exclusion criteria
Exclusion criteria: ? Patient with diabetes mellitus ? Patients who have received metformin or another mTOR inhibitor in the last 2 years ? Patients with deranged liver or renal profile ? Patients with known hypersensitivity to metformin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prolonging progression free survivalTimepoint: patients will be followed for 1 year and time to relapse will be noted | — |
Secondary
| Measure | Time frame |
|---|---|
| i) To evaluate response rate in two arms ii) To study the toxicity profile in two groups iii) To evaluate overall survival in two groups iv) To compare the Quality of life between two groups Timepoint: 1 year | — |
Countries
India
Contacts
Public ContactSaphalta Baghmar
Outcome results
None listed