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Strategic preoperative fentanyl administration before general anaesthesia for holistic perioperative analgesia

Critical Evaluation Of Pre-Induction Fentanyl As â??Perioperativeâ?? Analgesicâ?? In Patients Undergoing Laparoscopic Surgery:An Evolving Concept Or Imminent Need?

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2012/01/002391
Enrollment
300
Registered
2012-01-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- perioperative pain during laparoscopic surgery

Interventions

Intervention1: 3 modes of equidose(3mcg/kg) intravenous preanaesthetic induction fentanyl dosing. Group I will recieve single intravenous bolus dose . Group II will recieve 3 divided intermittent
Group I will recieve single intravenous bolus dose of fentanyl 3mcg/kg Group II will 3 divided intermittent intravenous boluses(0,3,6 minutes)of fentanyl 1mcg/kg per bolus(total dose 3mcg/kg) G
Group I will recieve single intravenous bolus dose of fentanyl 3mcg/kg Group II will 3 divided intermittent intravenous boluses(0,3,6 minutes)of fentanyl 1mcg/kg per bolus(total dose 3mcg/kg) Group

Sponsors

Department of Anaesthesiology Pain and Perioperative Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Male or female gender 2.Aged 20-70 years 3.Scheduled surgery: Laparoscopic surgery (30-minutes to 150- minutes) 4.General anaesthesia 5.Elective nature of intervention 6.Consenting for surgery

Exclusion criteria

Exclusion criteria: 1. Patients with uncompensated systemic co-morbidity [cardiac (hypertension, coronary artery disease, cardiomyopathy, arrhythmias), respiratory (bronchial asthma, COPD), endocrinology (diabetes mellitus, thyroid disease), hepato-renal, CNS 2. Allergy to opioid drugs 3. History of substance abuse 4. Psychiatric illness 5. Any previous history of respiratory depression with opioids

Design outcomes

Primary

MeasureTime frame
1.The impact of three equi-dose pre-induction IV fentanyl dosing strategy on indices related to prevailing â??balanced anaesthesiaâ?? concept. 2.Analysis of best pre-induction fentanyl dosing strategy in terms of balanced anaesthesia, postoperative analgesia and side-effects reduction.Timepoint: From first dose of fentanyl to 48 hrs time point—

Secondary

MeasureTime frame
nilTimepoint: nil—

Countries

India

Contacts

Public ContactDr Nitin Sethi

Department of Anaesthesiology Pain and Perioperative Medicine Sir Ganga Ram Hospital

duttaamitabh@yahoo.co.in01142252513

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026