Does Dexmedetomidine[a sleep inducing drug] prevent injection pain due to Propofol [an anaesthetic drug]?- a study

Double blind placebo controlled study: To evaluate whether Dexmedetomidine reduces Propofol injection pain.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2012/01/002364

Enrollment

100

Registered

2012-01-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients coming for surgery under general anaesthesia

Interventions

Intervention1: Dexmedetomidine: 0.5 microgram/kg of intravenous Dexmedetomidine injected at a rate of 0.5ml/sec after applying tourniquet, then tourniquet released,IV Propofol 3ml given Intervention2:

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II patients undergoing general anaesthesia

Exclusion criteria

Exclusion criteria: paediatric patients ASA III and IV patients patients allergic to Dexmedetimidine Neuropsychiatric patients

Design outcomes

Primary

Measure	Time frame
proportion of patients attaining pain relief for injection pain due to propofolTimepoint: 5min	—

Secondary

Measure	Time frame
proportion of patients showing reduced withdrawal movements to propofol injectionTimepoint: 5min	—

Countries

India

Contacts

Public ContactDr Uday Ambi

S N Medical college

udayambi@ymail.com9880570780

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026