Health Condition 1: null- HIV & TB
Conditions
Interventions
Intervention1: Early intiation of HAART: HAART starting within 2-4 weeks of commencement of antituberculosis treatment (ATT) for 12 months
Intervention2: Early intiation of ART: ART starting within 2-
Sponsors
National AIDS Control Organization
Eligibility
Inclusion criteria
Inclusion criteria: Subjects aged over 18 years, who had seven or fewer days of cumulative previous ART (unless taken during pregnancy to prevent mother-to-child-transmission), and who had not started ATT or received less than 14 days of the same, were eligible for entry into this study. Both confirmed and probable diagnoses of TB were permitted for inclusion.
Exclusion criteria
Exclusion criteria: Exclusion criteria were pregnancy, concomitant diabetes mellitus, epilepsy, severe illness (e.g. loss of consciousness, severe hempotysis etc.), and multi-drug resistant TB (MDR - TB).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary end points of the study were death from any cause and antiretroviral treatment failure, as a measure of progression of HIV disease.Timepoint: April, 2006 to March 2011 | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary end points of the study were defined by safety and tolerability of ARV therapy, as assessed by the incidence of adverse events and proportion of subjects changing/ discontinuing ARV therapy because of the same.Timepoint: April, 2006 to March 2011 | — |
Countries
India
Contacts
Public ContactDr Sanjeev Sinha
AIIMS
Outcome results
None listed