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Early versus Late start of dialysis in patients with acute kidney failure

Randomized controlled trial of "prophylactic" vs "as and when indicated" dialysis in acute kidney injury

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2011/12/002255
Enrollment
200
Registered
2011-12-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Acute Kidney Injury

Interventions

Intervention1: Prophylactic dialysis: Prophylactic dialysis will be initiated if Blood urea nitrogen and/or serum creatinine increases above 70 mg/dl and 7 mg/dl respectively. Patients in control grou

Sponsors

Seth GS Medical college and KEM Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients referred for nephrology consultation meeting following criteria will be eligible for inclusion: • Patients of either sex more than 12 years of age willing to consent • Patients with threefold increase in the serum creatinine or GFR decrease by 75 percent or urine output of

Exclusion criteria

Exclusion criteria: • Patients needing emergency dialysis which will include: -Refractory fluid overload -Hyperkalemia >6mEq/l unresponsive to medical management -Signs of uremia, such as pericarditis, neuropathy, or an otherwise unexplained decline in mental status -Metabolic acidosis (pH less than 7.1) • Patient under 12 years of age • Unwilling to consent

Design outcomes

Primary

MeasureTime frame
renal and patient survivalTimepoint: hospital stay

Secondary

MeasureTime frame
time to renal recovery, bleeding, infections and nutritional statusTimepoint: hospital stay

Countries

India

Contacts

Public ContactTukaram Jamale

Dept of Nephrology, Seth GSMC, KEM Hospital

tukaramjamale@yahoo.co.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026