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Effect of zinc supplementation in children with cystic fibrosis

Role of zinc supplementation in children with cystic fibrosis: randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2011/12/002230
Enrollment
32
Registered
2011-12-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Children suffering from cystic fibrosis

Interventions

Intervention1: Tablets of zinc: Enrolled subjects will get dispersible tablets containing zinc (30 mg) daily for a period of 12 months Control Intervention1: Placebo: Enrolled children will get simila

Sponsors

Indian Council of Medical Reaserch
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children above the age of 5 years of either sex with cystic fibrosis (diagnosis based on two abnormal sweat chloride of > 60 mEq/l on two occasions in children with clinical features suggestive of cystic fibrosis).

Exclusion criteria

Exclusion criteria: 1.Children who are not willing to come for regular follow up. 2.Children who are on any zinc supplementation in last one month.

Design outcomes

Primary

MeasureTime frame
Average days of systemic antibiotics in the two groups over one year.Timepoint: At enrolment and end of one year

Secondary

MeasureTime frame
1.Difference in FEV1 at 3, 6, 9 and 12 months in children above 5 years of age as measured by spirometry 2.Difference in colonization of airways with pseudomonas at 3, 6, 9 and 12 months Timepoint: At enrolment (Base line), 3, 6, 9 and 12 months

Countries

India

Contacts

Public ContactDr S K kabra

All India Institute of Medical Sciences

skkabra@hotmail.com1126594610

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026