Health Condition 1: null- aggressive periodontitis
Conditions
Interventions
Intervention1: mishal: pg student
Intervention2: inersan (probiotic): atleast 1 billion CFU l. brevis to be taken twice daily for 14 days
Control Intervention1: doxycycline + inersan: to be taken twic
Sponsors
Jagadguru Shree Shivarathreeswara dental college and hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age group of 14 - 35 years, both males and females 2. Sites with probing depth more than 5 mm 3. Loss of clinical attachment level more than 5 mm
Exclusion criteria
Exclusion criteria: 1. Debilitating systemic disease 2. Received antibiotics or anti-inflammatory drugs during the 6 months prior to the study 3. Received periodontal therapy during the 6 months to 1 year prior to the study 4. Lactose intolerance 5. Allergy to Microdox (Doxycycline) or Inersan (Probiotics) 6. Pregnancy 7. Lactating women 8. Smokers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluation of which of medications are effective in improving clinical parameters (plaque index, gingival index, probing pocket depth and clinical attachment level) and reducing the A. actinomycetemcomitans count. Timepoint: baseline, 2 weeks, 2 months, 5 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the periodontal tissue response to probiotic alone, probiotic + doxycycline and doxycycline alone by recording clinical parameters like plaque index, gingival index, probing pocket depth and clinical attachment level and effect on Lactobacilli and periodontal pathogen A. actinomycetemcomitans. Timepoint: baseline, 2 weeks, 2 months, 5 months | — |
Countries
India
Contacts
Public ContactDr Mishal Piyush Shah
jss dental college and hospital
Outcome results
None listed