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A clinical trial to study the effect of two drugs, triamcinolone and methylprednisolone injection in patients with capillary hemangioma (malformation of blood vessels)

SAFETY AND EFFICACY OF INTRALEISONAL STEROIDS IN THE MANAGEMENT OF PERIOCULAR CAPILLARY HEMANGIOMAS OF CHILDHOOD

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2011/11/002169
Enrollment
16
Registered
2011-11-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Periocular capillary hemangioma

Interventions

Intervention1: Injection methylprednisolone intralesional: Injection methylprednisolone 40 mg single injection Control Intervention1: Injection of mixture of injection triamcinolone and injection beta

Sponsors

Post Graduate Institute of Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The patients less than 7 years of age Patients with periocular capillary haemangioma Patients with visual loss due to proptosis, blepharoptosis, astigmatism, strabismus or optic nerve compression Patients seeking treatment of periocular hemangioma for cosmetic reasons Patients who have not recieved any treatment for periocular hemangioma prior to presentation

Exclusion criteria

Exclusion criteria: Very large periocular lesion such as lesion with extension outside the orbit or intracranial extension. Patients who have received any form of treatment for haemangioma prior to presentation Children more than seven years of age as lesions tend to disappear by itself in majority of such patients. Patients not fit for general anaesthesia because of any systemic reason

Design outcomes

Primary

MeasureTime frame
Mass regressionTimepoint: 1 month 3 months 6 months

Secondary

MeasureTime frame
Improvement in blepharoptosis Improvement in proptosis Change in astigmatismTimepoint: 1 month 3 months 6 months

Countries

India

Contacts

Public ContactDr Nishant Gupta

Department of Ophthalmology PGIMER Chandigarh

itsdrpankaj@hotmail.com1722747837

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026