Health Condition 1: null- Interstitial lung disease
Conditions
Interventions
Intervention1: Doxycycline antibiotic: It is generally used 100 mg twice daily orally after one hour of taking meals.
It is used at least for 6 months.
Control Intervention1: No comparator is needed
Sponsors
Institute of Pulmocare Research
Institute of Pulmocare Research
Eligibility
Inclusion criteria
Inclusion criteria: 1. Willing to give written informed consent 2. Clinically suspected patients with ILDs with the diagnosis being substantiated through chest X-ray(PA) and HRCT chest.
Exclusion criteria
Exclusion criteria: 1.History of exacerbation in past 1 month 2.History of Doxy allergy 3.Having any obvious contraindication for Doxycycline 4.Unable to meet the demand of the protocol for any reason 5.Significant abnormality in liver or renal function 6. Feature of chronic congestive cardiac failure (supported by echocardiography) 7.Known case of Idiopathic pulmonary disease with cardiovascular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| At least no detoriation than before in subjective wellbeing of the patient and clinicoradiological and ±FVC changes.Timepoint: Between 12 weeks and 6 months after starting doxycycline with repeat spirometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Not applicable | — |
Countries
India
Contacts
Public ContactDr Parthasarathi Bhattacharyya
Institute of Pulmocare & Research
Outcome results
None listed