Does Escitalopram helps in early recovery and prevent relapse in cases of idiopathic central serous retinopathy which causes blister like elevation at the centre of retina causing loss of vision

Early recovery and prevention of relapse in patients with idiopathic central serous retinopathy in out patient retina clinic - A pragmatic randomized controlled trial of oral SSRI vs placebo.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2011/11/002148

Enrollment

110

Registered

2011-11-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Idiopathic Central serous retinopathy

Interventions

Intervention1: Escitalopram: oral

5mg OD for 6 months Control Intervention1: Placebo: oral

5mg OD for 6 months

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with primary idiopathic serous retinopathy (ICSR) coming to retina clinic of KIMS for the first time. 2. Patients with primary ICSR received treatment elsewhere (without adequate SSRI exposure). 3. The patient with primary ICSR with medical co-morbidity not directly associated with manifestation of CS

Exclusion criteria

Exclusion criteria: 1. Patients with secondary CSR 2. Past history of SSRI exposure 3. Non-consent.

Design outcomes

Primary

Measure	Time frame
Relapse of ICSRTimepoint: Relapse of ICSR within 6 months; check up at least every month	—

Secondary

Measure	Time frame
1.Visual acquity 2.Retinal pigment epithelial abnormalityTimepoint: 6 months	—

Countries

India

Contacts

Public ContactDrGNageswar Rao

Kalinga Institute of Medical sciences

drgnagesh@yahoo.com09437170193

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026