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A clinical trial to compare the efficacy of 7-day and 14-day triple drug therapy for the eradication treatment of Helicobacter pylori infection

Comparison of 7-day and 14-day triple therapy for Helicobacter pylori eradication-A randomized controlled trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2011/11/002139
Enrollment
320
Registered
2011-11-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with symptomatic Helicobacter pylori infection

Interventions

Intervention1: Amoxicillin 1000mg Clarithromycin 500mg Pantoprazole 40mg: These drugs will be given as twice daily for 7 days for one group and 14 days for other group Intervention2: Amoxicillin 1000m

Sponsors

Pradeep Kumar P
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with symptomatic H.pylori infection as evidenced by standard diagnostic methods.

Exclusion criteria

Exclusion criteria: 1) Age 18 years 2) Use of proton pump inhibitors in the last 1 week 3) Use of antibiotics in the last 4 weeks 4) Patients with allergy to any of the drugs used in the trial 5) Pregnant and breast feeding women 6) Patients with advanced chronic hepatic or renal disease 7) Previous history of H.pylori eradication therapy

Design outcomes

Secondary

MeasureTime frame
Various endoscopic findings in patients with symptomatic H.pylori infection Factors influencing successful eradication treatment Symptomatic improvement following eradication therapyTimepoint: six months

Primary

MeasureTime frame
Efficacy of H.pylori eradication assessed by stool antigen assayTimepoint: Efficacy of H.pylori eradication assessed by stool antigen assay

Countries

India

Contacts

Public ContactPradeep Kumar P

Government Medical College Hospital, Thiruvananthapuram

pksoli@yahoo.co.in9447005706

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026