Health Condition 1: null- Patients presenting with clinically diagnosed superficial epithelial microsporidial keratitis or keratoconjunctivitis.
Conditions
Interventions
Intervention1: Debridement: Debridement of all the lesions will be done using a sterile no. 15 blade on a Bard-Parker handle for patients in the debridement group (arm). Corneal scrapings will be sub
Sponsors
Hyderabad Eye Research Foundation
Eligibility
Inclusion criteria
Inclusion criteria: Patients presenting with clinically diagnosed superficial epithelial microsporidial keratitis or keratoconjunctivitis. Minimum of 10 discrete epithelial or subepithelial lesions on presentation. Must be able to read and sign an informed consent form or if the patient is under 18 years of age, the informed consent must be understood and signed by the patient?s parent or guardian. Must agree to ensure compliance with the visit schedules and/or other requirements of the study, or the parents or guardians of patients less than 18 years of age must agree to ensure the above compliance.
Exclusion criteria
Exclusion criteria: Any clinically diagnosed case of superficial microsporidial keratoconjunctivitis with less than 10 discrete lesions. Presence of stromal infiltrates at presentation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time taken from the presentation to complete resolution of the clinical signs and symptoms (resolution is defined as absence of corneal lesion).Timepoint: All patients will be examined on day 0, 3, 7 and at weekly intervals until resolution of clinical signs and symptoms. | — |
Secondary
| Measure | Time frame |
|---|---|
| Final visual acuity following resolution of symptoms. Residual corneal scarring. Side-effects, if any.Timepoint: All patients will be examined on day 0, 3, 7 and at weekly intervals until resolution of clinical signs and symptoms. | — |
Countries
India
Contacts
Public ContactSavitri Sharma
L. V. Prasad Eye Institute
Outcome results
None listed