Health Condition 1: null- Newborns with suspected sepsis
Conditions
Interventions
Intervention1: CRP: Serial qCRP in Culture positive who happened to have received sensitive antibiotic versus culture positive who happened to have received resistant antibiotics versus culture steril
Sponsors
Postgraduate institute of Medical Education and Reasearch
Dr Praveen Kumar
Eligibility
Inclusion criteria
Inclusion criteria: Infants from 0-28 days of life admitted in Newborn Unit of PGIMER with 1. Clinically suspected sepsis, AND 2. Whose quantitative CRP (qCRP) prior to start of antibiotics is > 10 mg/L.
Exclusion criteria
Exclusion criteria: The following patients will be excluded: Subjects who have 1. Undergone surgery in the previous 7 days 2. Birth trauma 3. Major or life-threatening congenital malformations 4. Clinically suspected or serologically proven intra-uterine infection 5. Antibiotics in preceding 48 hours, unless those antibiotics happened to be proven resistant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A) Key outcome: Quantitative CRP at 48 hours. Timepoint: 48 hr from enrollment | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes: 1. Quantitative CRP at 24 and 36 hr. 2. SNAP-II score remission category at 48 hours.Timepoint: 48 hours from enrollment | — |
Countries
India
Contacts
Public ContactDr sandeep S Patil
PGIMER
Outcome results
None listed