Health Condition 1: null- Term new borns with perinatal asphyxia
Conditions
Interventions
Intervention1: Hypothermia
: Babies will be cooled using cloth covered cooling gel packs to achieve a target temperature of 33°C-34°C. This temperature will be maintained by continuous rectal and s
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: Inborn babies with (1,2,3 + Any one of 4 ) 1. Gestational, age >= 37 weeks 2. ABG(umbilical cord or 1st postnatal hour pH = 12meq 3. APGAR 4. Any one of the following i. Evidence of encephalopathy (THOMPSON SCORE >5) ii. Evidence of fetal distress iii. Assisted ventilation for at least 10 min after birth iv. Evidence of any organ dysfunction v. History of acute perinatal event- intrapartum fetal distress, cord prolapsed, placental abruption ,uterine rupture, maternal trauma, cardiac arrest
Exclusion criteria
Exclusion criteria: i. Infants >6 hours of age at the time of randomisation ii. Major congenital abnormalities iii. If the baby does not establish spontaneous respiration by 20 minutes iv. Out born babies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DNA DAMAGE AT 72 HOURS OF LIFE DEVELOPMENTAL FOLLOW UP TILL ONE YEAR OF AGETimepoint: DNA DAMAGE AT 72 HOURS OF LIFE | — |
Secondary
| Measure | Time frame |
|---|---|
| DEVELOPMENTAL FOLLOW UP TILL ONE YEAR OF AGETimepoint: one year | — |
Countries
India
Contacts
Public ContactDr Vishnu Bhat
JIPMER
Outcome results
None listed