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COMPARATIVE STUDY OF EFFECT OF VAPOCOOLANT SPRAY & EMLA CREAM ON PAIN IN INFANTS

COMPARATIVE STUDY OF EFFECT OF VAPOCOOLANT SPRAY & EMLA CREAM ON PAIN DUE TO DPT VACCINATION IN INFANTS OF 6 WEEKS- 3 MONTHS OF AGE

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2011/10/002061
Enrollment
90
Registered
2011-10-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: EMLA Cream,Breast Feeding : 1 gm of EMLA cream will be applied at the site of injection that will be covered with the occlusive dressing (Tegaderm, 3M) for approximately 60 minutes. The
a water soluble marker (sketch pen) will use to mark four dots on the skin where the cream has been applied, same time infant will be allowed to breastfeeding. 0.5 ml of whole cell DPT vaccine (wDPT),

Sponsors

Deppt of Pediatrics LLRM Medical College Meerut
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Full term healthy infants, less than 3 months of postnatal age, either exclusive or partial breast fed, who will attend the immunization clinic for first DPT vaccination according to universal immunization programme.

Exclusion criteria

Exclusion criteria: 1. All infants who have required hospital stay for more than 48 hrs 2. Perinatal asphyxia ( 5 mins apgar score less than 7) or delayed cry if born at home 3. IUGR wt less than 10th percentile for gestational age 4. Pre- term deliveries ( less than 37 weeks of gestation) 5. Previous surgery

Design outcomes

Primary

MeasureTime frame
Duration of cry after vaccinationTimepoint: Immediately and after 1 and 3 mins of niddle insertion

Secondary

MeasureTime frame
1.Latency of cry 2. modified facial coding score/ FLACC score/ Neonatal Infant pain scaleTimepoint: Immediately and after 1 and 3 mins of niddle insertion

Countries

India

Contacts

Public ContactDr Ajeet Dwivedi

Deptt. of Pediatrics, LLRM Medical college meerut

anuamit7@rediffmail.com9837405009

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026