A clinical trial to study the effect of clindamycin in patients with vaginal pH MORE THAN OR EQUAL TO 5 to prevent pretermlabour

Oral Clindamycin for prevention of preterm labour in pregnancies of 13 to 16 plus minus 1 week with vaginal pH more than or equal to 5.A randomized double blind placebo controlled trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2011/10/002045

Enrollment

264

Registered

2011-10-11

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- pregnancy Health Condition 2: O600- Preterm labor without delivery

Interventions

Intervention1: CLINDAMYCIN and Placebo: Clindamycin 300mg BD for 5 days Placebo starch filled in gelatin capsules BD for 5 days Intervention2: Clindamycin: 300 mg BD 5 days Control Intervention1: Plac

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant women 13 to 16 plus minus 1 week period of gestation. Singleton pregnancy vaginal pH more than or equal to 5

Exclusion criteria

Exclusion criteria: Not willing to provide informed concent History of antibiotic use with in the previous 14 days Current placement of cervical cerclage Current recepit of tocolytic therapy History of cone biopsy Significant known medical complications diabetes, renal disease, collagen disease, epilepsy, lupus, antiphospholipid syndrome, essential hypertention Uterine or cervical anomaly Life threatening known fetal anomaly

Design outcomes

Primary

Measure	Time frame
preterm labourTimepoint: preterm labour	—

Secondary

Measure	Time frame
low birth weight , misscarriagesTimepoint: low birth weight , misscarriages	—

Countries

India

Contacts

Public ContactDr PALLAVI CHALASANI

KLE university

mbbellad@hotmail.com09164258939

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026