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The impact of preinduction fentanyl dosing strategy on postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: A concept evaluation of equi-dose fentanyl given as a single-bolus or divided intermittent boluses or continuous infusion administration technique

The impact of preinduction fentanyl dosing strategy on postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: A concept evaluation of equi-dose fentanyl given as a single-bolus or divided intermittent boluses or continuous infusion administration technique

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2011/091/000227
Enrollment
270
Registered
2011-02-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Problem reduction

Interventions

Intervention1: 3 modes of equidose intravenous preanaesthetic induction fentanyl dosing: nil Control Intervention1: nil: nil

Sponsors

Dr Amitabh Dutta
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Male or female gender 2.Aged 20-60 years age 3.Scheduled surgery: Laparoscopic cholecystectomy 4.General anaesthesia 5.Elective nature of intervention 6. Consenting for surgery

Exclusion criteria

Exclusion criteria: 1.Patients with uncompensated systemic co-morbidity [cardiac (hypertension, coronary artery disease, cardiomyopathy, arrhythmias), respiratory (bronchial asthma, COPD), endocrinology (diabetes mellitus, thyroid disease), hepato-renal, CNS 2. Allergy to opioid drugs 3. History of substance abuse 4. Psychiatric illness 5. Acute nature of gall bladder pathology (cholecystitis) 4. Those with a tendency/recent history of hyperemesis

Design outcomes

Primary

MeasureTime frame
The impact of pre-induction IV fentanyl dosing methodology on reduction of PONV incidenceTimepoint: Time of extubation to 48 hours postop or patient discharge from the hospital whichever is later

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr. Nitin Sethi

Department of Anaesthesiology, Pain and Perioperative Medicine Sir Ganga Ram Hospital, Old Rajinder Nagar ,New Delhi

duttaamitabh@yahoo.co.in01142252513

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026