None listed
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Dr. Ajay Puri,
Professor & Surgeon,
Bone & Soft Tissue Dept.,
Tata Memorial Hospital,
Dr. Ernest Borges Marg,
Parel, Mumbai 400 012
Contact no.- 91-22-2417 7000 Ext. 4295
E-mail: docpuri@gmail.com
Eligibility
Inclusion criteria
Inclusion criteria: Preclinical Phase: a)Patients with high-grade sarcoma undergoing amputation surgery b) Patients where histological evaluation of necrosis is not required for management. Clinical Phase: All diaphyseal tumors where resection is possible with a wide margin and reconstruction possible with available implants
Exclusion criteria
Exclusion criteria: Preclinical phase: a)Patient not undergoing amputation or palliative surgery, b) Low grade tumor c) Patients where histological evaluation of necrosis is required for treatment Clinical Phase a) Cases where Resection with wide margin is not possible, b) Tumor extent such that reconstruction is not possible with available implants c) Resections that would involve removal of the articular surface
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Histological changes in the tumor tissue caused by pasteurization and efficacy of pasteurization technique in killing malignant bone tumour cells.Timepoint: 1 year. | — |
Secondary
| Measure | Time frame |
|---|---|
| The effect of pasteurization on the mechanical and osteoinductive properties of treated bone. This will be done by the clinical study on 10 patients to study the clinical efficacy in terms of time to incorporation and local control.Timepoint: 1 year. | — |
Countries
India
Contacts
Public ContactDr. Ashish Gulia
Outcome results
None listed