Health Condition 1: null- Chronic Obstructive Pulmonary Disease Health Condition 2: J441- Chronic obstructive pulmonary disease with (acute) exacerbation
Conditions
Interventions
Intervention1: Metered dose inhaler containing Ciclosonide 200 mcg, Tiotropium Bromide 9 mcg and Formoterol 6 mcg: Drug will be given one puff once a day for 3 months
Control Intervention1: Metered do
Sponsors
Research project grant of Government of Gujarat
Eligibility
Inclusion criteria
Inclusion criteria: Age between 35 to 70 years of either sex Clinically diagnosed mild to moderate COPD as per GOLD guideline (FEV1 more than 50 FEV1 and FVC ratio less than 0.7) Ability to give written informed consent Smokers and ex-smokers more and equal to 10 pack per years
Exclusion criteria
Exclusion criteria: Patients on oral steroid History Of significant illness of other system especially cardiovascular system History of exacerbation in run in period Patients having other serious respiratory illness ( tuberculosis asthma) other than COPD History of long acting antihistaminic within 1 week History of Hypersensitivity to study medications Contraindication to six minute walk test Do not give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function test (FEV1 and FVC)Timepoint: Prospective | — |
Secondary
| Measure | Time frame |
|---|---|
| Six minute walk distance (6MWD)Timepoint: Prospective | — |
Countries
India
Contacts
Public ContactDr CB Tripathi
GMC BHAVNAGAR
Outcome results
None listed