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Dexmedetomidine infusion during laparoscopic bariatric surgery improves airway reflexes and hemodynamic outcome at tracheal extubation: A prospective, randomized, controlled study.

Dexmedetomidine infusion during laparoscopic bariatric surgery improves airway reflexes and hemodynamic outcome at tracheal extubation: A prospective, randomized, controlled study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2011/091/000043
Enrollment
50
Registered
2011-01-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Dexmetedomidine: 1ug/kg bolus followed by 0.5ug/kg/hr followed by 0.25/kg/hr prior to extubation and in postoperative period. Control Intervention1: Fentanyl: 1ug/kg bolus followed by 0

Sponsors

Max Super Speciality Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Body Mass Index (BMI) >35 kg/m2, 2. Patient either male or female with Age between 18-60 years posted for elective laparoscopic bariatric surgery.

Exclusion criteria

Exclusion criteria: Patients with severe COPD, heart block, bradycardia, hepatic impairment, 2. Allergy to dex and sulpha drugs, fentanyl, propofol and eggs, 3. Obvious difficult airway 4. Gastro-esophageal reflux.

Design outcomes

Primary

MeasureTime frame
PRIMARY OUTCOME: Our primary Outcome will be to assess the incidence of cough at tracheal extubationTimepoint: Number of coughing episodes at emergence /extubation(coughing as a 5 point scale)—

Secondary

MeasureTime frame
SECONDARY OUTCOME: The secondary outcome will be to determine the awakening time, hemodynamic parameters and pain score at tracheal extubation.Timepoint: Richmond Agitation and Sedation Score (RASS) Mean Arterial Pressure and heart rate at extubation Pain Score—

Countries

India

Contacts

Public ContactAparna Sinha

Max Suoer Speciality Hospital

apsin@hotmail.com01141320023

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026