None listed
Conditions
Interventions
Intervention1: Hemodynamic changes in neonates with septic shock: Leht ventricular output, right ventricular output, Ejection fraction, LA:Ao ratio, E/A ratio, Celiac artery flow, Middle cerebral arte
Sponsors
PGIMER Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: Septic shock diagnosed according to the modified International Consensus Conference on Pediatric Sepsis criteria for cardiovascular dysfunction
Exclusion criteria
Exclusion criteria: 1. Hypovolumic shock. 2. Baby diagnosed or suspected to have congenital heart disease. 3. Baby already on inotropes. 4. Severe birth asphyxia with evidence of HIE II or III in term/near-term neonates of &#61619;35 weeks (Sarnat staging) or mild/moderate/severe encephalopathy (Levene classification) in preterm neonates of <35 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of various hemodynamic parametersTimepoint: Baseline (before the start of inotropes in neonates with septic shock), baseline in controls | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in Leht ventricular output, right ventricular output, Ejection fraction, LA:Ao ratio, E/A ratio, Celiac artery flow, Middle cerebral artery flow after starting inotropes; in comparison to the baseline hemodynamic parametersTimepoint: Before addition/change of inotrope and after achieving hemodynamic stability | — |
Countries
India
Contacts
Public ContactDr Praveen Kumar
Outcome results
None listed