Health Condition 1: null- Attention Deficit Hyperactivity Disorder
Conditions
Interventions
Intervention1: Methylphenidate: Upto 1mg/kg/day for 8 weeks
Control Intervention1: Atomoxetine: Upto 1.2mg/kg/day for 8 weeks
Sponsors
Department of Psychiatry
Eligibility
Inclusion criteria
Inclusion criteria: Patients from 6 to 15 years of age with the diagnosis of Attention Deficit Hyperactivity Disorder according to Diagnostic and Statistical Manual of Mental Disorders-IV-Text Revision. Patients with moderate to severe illness as assessed by Clinical Global Impressions Severity Scale. Patients whose parents are willing to provide informed consent for participating in the study.
Exclusion criteria
Exclusion criteria: Patients with history of non-response or adverse drug reactions to methylphenidate or atomoxetine in the past. Patients who have taken any medication for ADHD in past one month. Patients with history of heart disease, seizures, bipolar affective disorder, psychotic illness, pervasive developmental disorder, substance abuse, anxiety, mental retardation or tic disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Vanderbilt ADHD Diagnostic Parent Rating Scale Score, Mean Vanderbilt ADHD Diagnostic Teacher Rating Scale Score, Mean Adverse Effect Checklist Score.Timepoint: Weekly assessments on Vanderbilt ADHD Diagnostic Parent Rating Scale and Adverse Effect Checklist for 8 weeks. Vanderbilt ADHD Diagnostic Teacher Rating Scale Assessment at baseline and 8 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean Clinical Global Impression Severity Scale ScoreTimepoint: 8 weeks;Mean Social Adjustment Inventory for Children and Adolescent ScoreTimepoint: 8 weeks | — |
Countries
India
Contacts
Public ContactDr Priti Arun
Government Medical College and Hospital
Outcome results
None listed