Health Condition 1: null- Depression
Conditions
Interventions
Intervention1: Community based Depression Intervention Programme (ComDIP): 1.Sertraline 50mg once daily as night dose prescribed by the Medical Officer of the Primary Health Centre
2.Home based Psycho
Sponsors
Dr InduPS
Dr Ramdas Pisharody
DrKAKumar
DrKVijayakumar
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age group 18-60 years 2. Permanent residents living in the area of MCH unit Pangappara for at least past 6 months 3. Diagnosis of moderate to severe depression 4. Informed consent to participate in the trial , to record examination findings and use the data in research and future publication 5. Literacy to read and write in Malayalam 6. Have an active phone number
Exclusion criteria
Exclusion criteria: Past or current diagnosis or history of treatment for bipolar disorder, dementia, psychosis 2. Currently being managed by a psychiatrist or psychologist 3. Taking any psychotropic drug 4. High risk of suicidality as measured by a suicidality score above 17 5. Pregnant, breastfeeding or planning to become pregnant in next 6 months 6. Seriously ill or bedridden patient 7. A woman who is not able to communicate with the health worker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remission of depression at 12 weeks as measured by 50% reduction in score from baseline in Hamilton Rating Scale for Depression ( HAM-D) or Montgomery Asberg Depression Rating Scale ( MADRS) or remission as per Mini Neuropsychiatric Interview (MINI) for DepressionTimepoint: 2 weeks, 4weeks, 8 weeks, 12 weeks Interim analysis will be done at 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| acceptabilityTimepoint: 2,6,8,12 weeks;Clinical Global Impression for Change or Improvement ( CGI-C / CGI-I)Timepoint: 2,6,8,12 weeks;Clinical Global Impression for Severity (CGI-S) scoreTimepoint: 2, 6, 8 and 12 weeks Interim analysis will be done at 8 weeks;Improvement in suicidality scoreTimepoint: 2 weeks, 6 weeks, 8 weeks, 12weeks;modified Global Assessment of Functioning (mGAF) scoreTimepoint: 2,6,8,12 weeks;treatment adherenceTimepoint: 2,6,8,12 weeks | — |
Countries
India
Contacts
Public ContactDr Indu P S
Govt Medical College, Trivandrum
Outcome results
None listed