Health Condition 1: null- Increased triglyceride (more than 300) and its implications with low high density lipoprotein cholesterol (males less than 40 and females less than 45)
Conditions
Interventions
Intervention1: Nicotinic Acid 1g Laropiprant 20mg: lipid lowering drug
Intervention2: laropiprant: 1.Dyslipidemia Nicotinic acid, Laropiprant,
Dose: Nicotinic acid 1 G, Laropiprant 20 mg
once daily Or
Sponsors
Sub arm study of PURSE HIS funded by Department of Science and Technology Government of India
Eligibility
Inclusion criteria
Inclusion criteria: Human participants attending cardiology op and PURSE-HIS study, of age group 18 to advanced age with isolated or combined hypertriglyceridemia of both sexes, who have given written informed consent to participate in the study and agree for all presaid examinations
Exclusion criteria
Exclusion criteria: Pregnant and lactating female participants. Hypersensitivity to the active substances or to the any of the excipients. Participants with significant or unexplained hepatic dysfunction. Active peptic ulcer disease. Arterial bleeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| achieving the target level (Triglyceride 150 and High density lipoprotein males40 and females 45) with minimal adverse effectsTimepoint: one year | — |
Secondary
| Measure | Time frame |
|---|---|
| acute vascular events, pancreatitisTimepoint: one year | — |
Countries
India
Contacts
Public ContactDr S Thanikachalam
Sri Ramachandra University
Outcome results
None listed