Health Condition 1: null- H.pylori gastric load
Conditions
Interventions
Intervention1: Extract of Glycyrrhiza glabra: One capsule (150 mg actives) per day for 60 days Compared with Placebo one capsule (0 mg actives) per day for 60 days
Control Intervention1: placebo: Comp
Sponsors
NICS CO LTD
Natural Remedies Pvt Ltd
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects aged 18 - 45 years 2. H. pylori 13C urea breath test (positive Greaterthan/Equalto 4.0 Plus/Minus 0.4 DOB) 3. H. pylori positive in stool test
Exclusion criteria
Exclusion criteria: 1. History/Diagnosed with bleeding duodenal ulcer 2. Advanced chronic illness that would impair follow-up or monitoring. 3. Pregnancy or breast feeding. 4. Previous surgery for ulcers. 5. History of MALT lymphoma 6. First level relatives of gastric cancer patients 7. Subjects with previous history of gastroesophageal reflux 8. Subjects with concomitant symptoms of the irritable bowel syndrome. 9. Drug and alcohol abuse. 10. Use of oral antibiotics and/or PPIs and/or H2-antagonists during the 2 weeks prior to ingestion of the study product 11. Patients using non-steroidal anti-inflammatory drugs, steroids, bismuth preparation 12. Mental illness or dementia. 13. Participation in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease in the H.pylori gastric load in the treatment group compared to placebo by change in the severity of symptomsTimepoint: 45 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in the severity of symptoms measured by 7-point likert scaleTimepoint: 60 days | — |
Countries
India
Contacts
Public ContactSanthosh Kumar
D2L Pharma Research Solutions
Outcome results
None listed