Health Condition 1: null- Schizophrenia Health Condition 2: F20- Schizophrenia
Conditions
Interventions
Intervention1: ELECTROCONVULSIVE THERAPY: 1. ECT machine used was microprocessor brief pulse constant current ECT
2. Bilateral temporal electrode placement
3. ECTs were given twice a week
4. Total num
Sponsors
Government Medical College and Hospital Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients in the age group of 16 to 65 years. 2. Patients suffering from schizophrenia as per ICD 10. 3. Patients who fulfilled the criteria for TRS. For the purpose of the study, TRS was defined according to the modified Kane et.al. criteria, which defines TRS as: a) At least two prior drug trials of at least 4-6 weeks duration at 400-600 mg of chlorpromazine (or equivalent) without significant clinical improvement. b) Persistent psychotic symptoms defined as a score of 45 on 18 item scale of BPRS and score of 4 (moderate) on at least two items of positive symptoms. c) The duration of illness should be at least one year. 4. Patients who were accompanied by reliable informants. 5. Patients and informants who were willing to participate in the study and who were ready to give consent for ECT and anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients who had associated medical problems, which could affect the course of illness as well as their fitness for general anesthesia. 2. Patients of co-morbid substance dependence except nicotine dependence. 3. Patients who had received ECT in the past one-year. 4. Patients who had received at least 4 ECT?s in the past without any significant improvement. 5. Patients who were intellectually deficient. 6. Patients having schizoaffective disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in score on the assessment scales namely Brief Psychiatric rating scale and Positive and negative syndrome scale for schizophrenia.Timepoint: Baseline After 4, 6 and at the end of ECT course. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in score on the Global assessment of functioning scale, Clinical global impressions and the World Health Organization Quality of life scale Brief version.Timepoint: Baseline and at the end of ECT course. | — |
Countries
India
Contacts
Public ContactDr Rohit Garg
Department of Psychiatry, GMCH, Sector 32, Chandigarh
Outcome results
None listed