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A clinical trial to compare the antioxidant enzymes(superoxide dismutase,catalase and peroxidase)in patients of retinoblastoma localised to the eye and retinoblastoma with distance spread(metastasis)

Comparision of oxidative stress between intraocular retinoblastoma and metastatic retinoblastoma group. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2011/08/001953
Enrollment
80
Registered
2011-08-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with intraocular and metastatic retinoblastoma

Interventions

Control Intervention1: The comparator/control/s being studied: metastatic retinoblastoma patients : Trial details: 40 consecutive patients of intraocular retinoblastoma were recruited for the study.

Sponsors

Regional Institute of ophthalmology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients with retinoblastoma with age ranging from newborn to 8 year were included.

Exclusion criteria

Exclusion criteria: 1. where written consent was not available from parents of the children 2.where the physical condition of the patient does not allow collection of blood sample by venepuncture.

Design outcomes

Secondary

MeasureTime frame
noneTimepoint: not applicable

Primary

MeasureTime frame
Activity of three antioxidant enzymes[superoxide dismutase,catalase,peroxidase] were measured from blood samples obtained from cases of intraocular retinoblastoma and cases of metastatic retinoblastoma.Timepoint: Activity of three antioxidant enzymes were measured from blood samples obtained from cases of intraocular retinoblastoma and cases of metastatic retinoblastoma once a week for the study duration.

Countries

India

Contacts

Public ContactDr Somnath Mukhopadhyay

Regional Institute of Ophthalmology,kolkata

himadri.datta@gmail.com91-9830127929

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026