Health Condition 1: 7- Osteopathic Health Condition 2: 7- Osteopathic Health Condition 3: null- Postoperative pain relief
Conditions
Interventions
Intervention1: Oral 120 mg oral etoricoxib tablet OD, scheduled as on the morning one hour before surgery and on next day, and placebo thrice day for 48 hours after operation.: Both will receive spina
Sponsors
Department of Anaesthesia and Intensive care
Eligibility
Inclusion criteria
Inclusion criteria: American society of anesthesiologist (ASA) I?II 18-70 years either sex elective total hip replacement or total knee replacement surgery under regional anaesthesia
Exclusion criteria
Exclusion criteria: ASA III-1V Known hypersensitivity to any of the drug under study Renal or hepatic insufficiency, History of asthma, chronic pain, recent gastro duodenal ulcer, coagulopathy, Previous cerebral vascular accident history Recent myocardial infarction (within 1 year)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure pain scores at rest and on movement on a 100 mm visual analogue scale (VAS)at 0,2,4,6,8,12,24 and 48 hours after admission to the post anaesthesia care unit and assuming a minimum relief of 20% reduction in VAS pain score on movement at the specified time mentioned Outcome Name: Postoperative pain reliefTimepoint: 02 years | — |
Secondary
| Measure | Time frame |
|---|---|
| Epidural local anaesthetic consumption in 48 hours,rescue analgesic consumption ,Side effects if any and patient satisfaction with pain control after 48 hoursTimepoint: 02 years | — |
Countries
India
Contacts
Public ContactDr Vanita Ahuja
Outcome results
None listed