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effect of aerobic exercise training in (diabetic peripheral neuropathy) patients with decreased sensation of foot as seen in diabetes

effect of aerobic exercise training in diabetic peripheral neuropathy : a randomised controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2011/07/001884
Enrollment
130
Registered
2011-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- diabetic polyneuropathy

Interventions

Intervention1: aerobic exercise: moderate intensity aerobic exercise training of 60- 70 % of Heart rate reserve, duration 45 min - 60 min for 3-5 days a week till 8 weeks Control Intervention1: standa

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult Type 2 diabetes with Distal Symmetrical Polyneuropathy 2.Type 1 diabetes with DPN above the age of 17 years 3.Ability to walk without assistance of devices

Exclusion criteria

Exclusion criteria: 1. A history or evidence on physical examination of significant central nervous system dysfunction (i.e., hemiparesis, myelopathy, and cerebellar ataxia) 2. Significant musculoskeletal deformity [i.e., amputation, scoliosis, abnormality of range of motion (ROM)] that would prevent participation 3. Lower extremity arthritis or pain that limits exercise. 4. A history or clinical evidence of severe cardiovascular disease that may limit or contraindicate exercise. 5. Symptomatic postural hypotension defined as a fall in blood pressure (i.e., >20 mm Hg for systolic or >10 mm Hg for diastolic blood pressure) in response to postural change, from supine to standing. 6. A history or evidence on physical examination of plantar skin pressure ulcer. 7. Patient unable to sense monofilament more than 6.65 SWM at baseline. 8. Patients Already being on treatment with drugs for neuropathy 9. Other forms of neuropathy being secondary to diabetes

Design outcomes

Primary

MeasureTime frame
nerve conduction velocity & Vibration Perception Threshold health related quality of life questionnaire Glycosated Hemoglobin PosturographyTimepoint: all the measures will be taken at base line, 4th week of exercise and 8th(last) week of exercise

Secondary

MeasureTime frame
posturography, monofilament,plantar pressure measurement via foot scannerTimepoint: baseline at the start of study, at 4 weeks and 8th week

Countries

India

Contacts

Public Contactsnehil dixit

Manipal university

snehildixit83@gmail.com918202574341

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 5, 2026