Health Condition 1: J219- Acute bronchiolitis, unspecified Health Condition 2: null- Bronchiolitis
Conditions
Interventions
Intervention1: oral zinc: 10 mg/day for children 6 months
20 mg/day for children 6 months
Duration: 7 days
Control Intervention1: Placebo: Identically looking and packaged inert tablets for 7 days
Sponsors
University College of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Children (between 3 months to 2 years) with a clinical diagnosis of severe bronchiolitis (inability to feed, severe distress,apnea, hypoxemia, lethargy or cyanosis)
Exclusion criteria
Exclusion criteria: 1) They were receiving or had received any micronutrient supplementation within last 4 weeks prior to onset of present illness. 2) Clinical evidence of underlying cardiac or chronic pulmonary disease 3) There is a co-morbid condition (severe malnutrition, meningitis) present at the time of admission. 4) There is lobar consolidation in chest x-ray. 5) Intubation/ventilation is required before enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Resolution of severe bronchiolitis (when lower chest retraction and the danger signs are no longer present) 2. Time to resolution of lower chest indrawing, fast breathing, inability to feed Timepoint: 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Recovery rate (proportion of children with resolution of severe bronchiolitis) 2. Duration of oxygen therapy 3. Duration of IV fluids 4. Duration of hospitalization Timepoint: 7 days | — |
Countries
India
Contacts
Public ContactDr Dheeraj Shah
Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital
Outcome results
None listed