To study and comparatively evaluate the ketamine-propofol with fentanyl-propofol combination for procedural sedation and analgesia in patients undergoing laparoscopic tubal ligation and to study which drug combination leads to an earlier recovery and discharge.

A RANDOMIZED CONTROL TRIAL OF KETAMINE-PROPOFOL AND FENTANYL-PROPOFOL COMBINATION FOR PROCEDURAL SEDATION AND ANALGESIA (PSA) IN LAPAROSCOPIC TUBAL LIGATION?

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2011/06/001850

Enrollment

100

Registered

2011-06-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- surgery under anesthesia

Interventions

Intervention1: ketamine-propofol: 0.5mg/kg body weight ketamine + 2mg/kg body weight propofol at the time of initiation of procedure followed by 0.5mg/kg propofol as required. Duration of procedure va

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria- American Society of Anesthesiologist physical status I patients aged 18-45 years female scheduled for laparoscopic tubal ligation. Exclusion Criteria- history of upper respiratory tract infections, asthma, allergy to propofol or ketamine, receiving treatment for psychiatric disease, receiving treatment for neuromuscular disease, seizure disorder, acid reflux, hiatus hernia, severe anemia, gross obesity, hepatic,cardiac or pulmonary disease.

Exclusion criteria

Exclusion criteria: Patients who have history of upper respiratory tract infections, asthma or allergy to propofol or ketamine or receiving treatment for any psychiatric or neuromuscular disease, patients with seizure disorder, acid reflux, hiatus hernia, severe anemia, gross obesity, hepatic, cardiac, or pulmonary diseases will be excluded from this study.

Design outcomes

Primary

Measure	Time frame
Measures patient recovery time and discharge time using Ketamine-Propofol And Fentanyl-Propofol Combination For PSA In Laparoscopic Tubal Ligation.Timepoint: November 2009 to March 2011	—

Secondary

Measure	Time frame
postoperative recovery and duration of hospital stay and comfort and acceptability in the two groups Timepoint: postoperative recovery and duration of hospital stay and comfort and acceptability in the two groups	—

Countries

India

Contacts

Public Contactdr ranju singh

professor

ranjusingh1503@yahoo.com09811151285

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026