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Study of usefulness of a new advanced diagnostic test to find out the causative organism in eye infection after surgery

Pilot study to examine utility of DNA macrochip in clinical management and outcomes in endophthalmitis - MOPES

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2011/04/001685
Enrollment
50
Registered
2011-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Endophthalmitis

Interventions

Intervention1: DNA macrochip test: PCR based diagnostic test for microbiological agent identification Control Intervention1: standard of care: Routine microbiology-microscopy and culture

Sponsors

Aravind Eye Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ? Acute endophthalmitis presenting within 1 month of intraocular surgery ? Chronic endophthalmitis occurring between 1 month-6 months of intraocular surgery

Exclusion criteria

Exclusion criteria: ? Previous treatment (excluding systemic) ? Vision PL or worse ? Corneal pathology/ other pathology affecting visualization or causing diminution of vision ? H/o trauma

Design outcomes

Primary

MeasureTime frame
1.Diagnostic efficiency of DNA macrochip and routine microbiology 2.Correlation between DNA macrochip and routine microbiology 3.Number of interventions in each group 4.Duration of hospital stay Timepoint: 3 months—

Secondary

MeasureTime frame
1.Visual results, 2.Anatomical Success 3.Clinical correlation Timepoint: 3 months—

Countries

India

Contacts

Public ContactAbhishek Kothari

Aravind Eye Hospital

dr.a.kothari@gmail.com09884017174

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026