None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Fever, headache, meningismus, other signs and clinical presentations of meningitis of more than 2 weeks duration. 2. Typical cerebrospinal fluid (CSF) features including pleocytosis with more than 20 cells, lymphocytes greater than 60%, protein greater than 100mg% and glucose level less than 60% of the corresponding blood glucose level. Presumptive diagnosis of TBM will be made based on the clinical criteria with typical CSF features and at least one of the following supporting criteria: 1. Radiographic findings based on chest X-ray that confirmed pulmonary TB (reticulonodular pattern in upper lobes with or without cavitatory lesions), 2. Hydrocephalous from brain computerized tomography (CT) scan, 3. Response to anti-tuberculous treatment after 4 weeks.
Exclusion criteria
Exclusion criteria: 1. The patients who already received more than 30 days of antituberculous drugs and steroids. 2. The patient declined to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Death or severe disability assessed by modified Rankin scaleTimepoint: | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Senior resident