Health Condition 1: null- Patients who are scheduled to undergo surgery and require awake nasal fibreoptic intubation in view of anticipated difficult oral intubation
Conditions
Interventions
Intervention1: dexmedetomidine 1µ
g/kg administered intravenously over 10 minutes prior to attempting awake nasal fibreoptic intubation:
Control Intervention1: Fentanyl 1µ
g/kg administered intravenously and midazolam 1mg intravenous prior to attempting awake nasal fibreoptic intubation:
Sponsors
Anitha Shenoy
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria : Patients of either gender aged above 18 years requiring awake nasal fibreoptic intubation
Exclusion criteria
Exclusion criteria: Exclusion Criteria: Patients with ASA physical status IV, raised intracranial pressure, uncontrolled seizure disorder / known psychiatric illness, receiving &#945;2 agonists/antagonists in the past two weeks, where either dexmedetomidine or benzodiazepine administration is contra-indicated and patients with acute unstable angina, laboratory confirmed acute myocardial infarction within the past 6 weeks, heart rate <50bpm, systolic blood pressure <90 mmHg, or complete heart block unless they have a pacemaker, patients with elevated liver enzymes > 2 times normal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fibrescopy score Intubation score Post intubation scoreTimepoint: At end of visualisation of glottis At point of intubation At end of intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Time for endoscopy and time for intubation Ease of endoscopy and intubation Number of attempts taken at endoscopy and intubation Postoperative patient satisfaction score Timepoint: At end of intubation process and 24 h after the surgical procedure | — |
Countries
India
Contacts
Public ContactUmesh Goneppanavar
Kasturba Medical College, Manipal
Outcome results
None listed