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A Study on Comparative Efficacy of Amitriptyline versus Propranolol in the Prophylaxis of Chronic Migraine

A Study on Comparative Efficacy of Amitriptyline versus Propranolol in the Prophylaxis of Chronic Migraine

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2010/091/002951
Enrollment
90
Registered
2011-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: amitriptyline: 10 mg once daily Control Intervention1: propranolol: 40 mg once daily

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients diagnosed with chronic migraine according to IHS criteria age > 10 years

Exclusion criteria

Exclusion criteria: patients with asthma, depression, anxiety, hypotension and mental retardation patients using anti convulsants, beta blockers, psychiatric drugs, MAO inhibitors

Design outcomes

Primary

MeasureTime frame
change in migraine score (M score)before and after therapy Timepoint: baseline data assessment and after 3 months therapy—

Secondary

MeasureTime frame
changes in disability associated with migraine and migraine associated symptoms before and after therapy changes in anxiety and depression before and after therapyTimepoint: baseline data assessment and after 3 months therapy—

Countries

India

Contacts

Public ContactDr. Thomas Iype
beenaiype@gmail.com09446230317

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026