A clinical trial to study the efficacy and safety of a regional block- bilateral superficial cervical plexus block using bupivacaine as the local anesthetic and clonidine as adjuvant with normal saline as control in patients undergoing elective thyroid surgery under general anesthesia

Safety and efficacy of bilateral superficial cervical plexus block in thyroidectomy - a double blind randomized controlled trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2010/091/002829

Enrollment

Registered

2010-12-15

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Conditions requiring elective thyroidectomy

Interventions

Intervention1: Bilateral superficial cervical plexus block: Bupivacaine 0.25% 30 ml total (75mg) Clonidine 1&micro

g/kg Control Intervention1: Bilateral superficial cervical plexus block: 30 ml of 0.9% Normal saline

Eligibility

Inclusion criteria

Inclusion criteria: Euthyroid patients Elective thyroidectomy under general anesthesia Either gender More than 18 years of age ASA class I and II

Exclusion criteria

Exclusion criteria: Unable to understand visual analog score and patient controlled analgesia Malignancy requiring block dissection Substernal goiters Contraindications to Bilateral superficial cervical plexus block Contraindications to morphine Sensitivity / Intolerance to local anesthetics / other medications used in the study Recent steroid or opioid or other analgesic use

Design outcomes

Primary

Measure	Time frame
Intraoperative fentanyl requirements and Total 24 hour postoperative morphine requirementsTimepoint: 24 hours	—

Secondary

Measure	Time frame
Visual Analog score at specific time intervals, First analgesic requirement time, Postoperative nausea and vomiting and antiemetic use, Side effects related to bilateral superficial cervical plexus block, morphine and clonidineTimepoint: Visual analog scores at 2, 4 ,6 8, 16 and 24 hours	—

Countries

India

Contacts

Public ContactKarthikeyan V S

sengkarthik@yahoo.co.in04132240475

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026