A clinical trial to study a technique of pain relief with different drugs for patients undergoing breast cancer surgery.

Ketamine as an adjunct with bupivacaine in paravertebral analgesia for breast surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2010/091/002826

Enrollment

Registered

2010-10-28

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Single shot paravertebral block

Group A: 0.25% bupivacaine 0.3ml/kg + ketamine 0.5mg/kg Control Intervention1: Single shot paravertebral block

Group B: 0.25% bupivacaine 0.3ml/kg

Eligibility

Inclusion criteria

Inclusion criteria: Breast cancer patients undergoing modified radical mastectomy, under 60 years of age, belonging ASA physical status 1 and 2

Exclusion criteria

Exclusion criteria: Patient refusal to participate, Local sepsis at the site of block, Severe chest wall deformity,Coagulopathy or patient receiving any anticoagulants, Known hypersensitivity to local anaesthetics.

Design outcomes

Primary

Measure	Time frame
Intra-operative fentanyl consumption, Post operative morphine consumption, Post operative pain scoresTimepoint: during surgery, at 0,2,6,12 and 24 hours in the post operative period	—

Secondary

Measure	Time frame
Post operative nausea and vomiting, pruritus, urinary retention, pnemothorax, respiratory depressionTimepoint: 24 hours post operative period	—

Countries

India

Contacts

Public ContactKrithika Krishnan

AIIMS

krithkris@gmail.com+919999227359

Outcome results