Skip to content

hypertonic saline in bronchiolitis

To compare the effect of nebulised 3% hypertonic saline (HS) with nebulised 0.9% normal saline in treatment of bronchiolitis in hospitalized children by a hospital based randomized, double-blind control trial.?

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2010/091/001227
Enrollment
250
Registered
2010-10-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: hypertonic saline nebulisation: as per study protocol Control Intervention1: normal saline nebulisation: as per study protocol

Sponsors

self
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children with bronchiolitis (defined by prodrome of upper respiratory tract infection, including rhinorrhea, cough, and sometimes low-grade fever, which progresses to lower respiratory tract involvement, paroxysmal cough and dyspnoea), with pulmonary score index >0 and ≤ 6

Exclusion criteria

Exclusion criteria: previous episode of wheezing; chronic cardiopulmonary disease; critical illness at presentation requiring admission to intensive care; or ventilatory support; the use of nebulised HS within the previous 12 hours; pulmonary score index > 6;

Design outcomes

Primary

MeasureTime frame
imrovement in psi scoreTimepoint: when psi score less than 3

Secondary

MeasureTime frame
reduction in hospital stayTimepoint: time taken to achieve study end points

Countries

India

Contacts

Public Contactdr. b. s. sharma

sms hospital

drbssharma@gmail.com01412563000

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026