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Clinical Trial to Evaluate intravenous esmolol hydrochloride infusion for postoperative analgesia in patients undergoing laparoscopic cholecystectomy

Evaluation of intravenous esmolol hydrochloride infusion for postoperative analgesia in patients undergoing laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2010/091/001113
Enrollment
100
Registered
2010-07-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: esmolol hydrochloride: 0.5mg/kg bolus followed by 10ug/kg/min infusion till surgery ends Control Intervention1: ringer lactate: same as interventional group

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: age 18-65 Patient undergoing laparoscopic cholecystectomy ASA I & II

Exclusion criteria

Exclusion criteria: 1. Age <18 years or > 65 years 2. ASA > II 3. History of hepatic, renal, or cardiac failure 4. Morbid obesity ( BMI > 40 kg/m2) 5. Chronic use of opioid or β-adrenergic receptor blocker 6. Known case of asthma or reactive airway disease 7. Severe mental impairment 8. Allergy to local anaesthetics 9. Inability to comprehend pain assessment 10. Patients with poorly controlled diabetes mellitus 11. Patients with organ transplant 12. Conversion to open cholecystectomy

Design outcomes

Primary

MeasureTime frame
To compare the effect of intraoperative intravenous esmolol hydrochloride infusion v/s placebo infusion (Ringer?s Lactate) along with fentanyl citrate on postoperative analgesia requirement in patients undergoing laparoscopic cholecystectomy.Timepoint: Till 12 hours postoperative—

Secondary

MeasureTime frame
To study the incidence of side effects occurring in the two groups in the study designTimepoint: Till 12 hours postoperative—

Countries

India

Contacts

Public Contactdr. rohit bansal
bansal.rohit81@gmail.com01642253845

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026