None listed
Conditions
Interventions
Intervention1: Stem Cells:
Control Intervention1: NIL: NA
Sponsors
Global Medical education & Research Center
Eligibility
Inclusion criteria
Inclusion criteria: Ages Eligible for Study: >21 Years Genders Eligible for Study: Both Accepts Healthy Volunteers: No ?Acute ST elevation on MI. ?CPK-MB above 2 times; upper reference value. ?Recanalised culprit vessel a) After successful PCI with stenting of culprit vessel. b) Reanalyzed vessel after thrombolytic therapy with no residual lesion or residual lesion of <50%. ?Hypokinetic, Akinetic, Dyskinetic segment assessed by 2D-Echocardigraphy in standard 16-segment model.
Exclusion criteria
Exclusion criteria: ? Multi vessel coronary artery disease (established). ? Previous MI with established significant Q-wave on ECG. ? Severe hepatic or renal dysfunction (Co-morbid Medical condition). ? Stroke with significant sequel. ? HIV/HBS/HCV positive serology. ? Short life expectancy due to cancer/ terminal illness which influence the patient. ? Mental disorder which interferes with possibility of Non-compliance with the protocol. ? Possibility of non-compliance with the protocol. ? Gross CCF/Pulmonary edema.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ? Improvement in LVEF perfusion measured by ECG, 2D-ECHO, Cardiac MRI, Coronary angiography.Timepoint: 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| ? Safety ? Improvement in myocardial function observed in SA node, AV node measured by ECG. ? Improved exercise time when observed on the 3rd and 6th month after the therapeutic procedure, when compare to exercise time before the administration of the therapeutic dose. ? Improvement in physical activity (Mild to Moderate), (Rest or Minimal to Mild). ? Reduction in the use of medicines. Timepoint: 3 , 6 and 12 months | — |
Countries
India
Contacts
Public ContactDr.lakshmi Kiran
Outcome results
None listed