A study to compare POsterolateral thoracotomy vs Nerve Sparing Thoracotomy for lung cancer surgery

Phase II Randomized trial comparing POsterolateral Thoracotomy versus Nerve Sparing Thoracotomy for lung surgery (PoTNeST) - Impact of preservation of the neurovascular bundle during thoractomy on post operative pain

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2010/091/000583

Enrollment

Registered

2010-06-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nerve Sparing Thoractomy: nil Control Intervention1: Conventional postero lateral thoractomy: nil

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing posterolateral thoracotomy for pulmonary resection, either primary lung malignancy or metastasis ECOG Performance status 0 or 1 Age between 18 and 75 years ASA Grade 1 or 2

Exclusion criteria

Exclusion criteria: Patients with previous thoractomy, patients who will have additional incisions (besides thoracotomy), patients on narcotic analgesics, anti inflammatory drugs and medications for neuropathic pain (anti convulsants, gabapentin and analogues, amytriptylin), unreliable for follow-up, previous radiotherapy, chest wall involvement, allergy to fentanyl or morphine, any contra-indication to paracetamol or diclofenac, patients not willing to use or unable to comprehend the use of patient-controlled analgesia

Design outcomes

Primary

Measure	Time frame
Mean maximum postoperative pain scoreTimepoint: first three postoperative days	—

Secondary

Measure	Time frame
Analgesic requirementsTimepoint: first 3 days;Incidence of chronic post thoractomy painTimepoint: 6 months;Mean pain scoreTimepoint: first three postoperative days	—

Countries

India

Contacts

Public ContactDr C S Pramesh

Tata Memorial Hospital

cspramesh@gmail.com02224177070

Outcome results