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A clinical trial to study the effect of two kinds of dressings papaya and hydrogen peroxide in patients with wound gape.

Comparison of safety and efficacy of papaya dressing with hydrogen-peroxide dressing on wound bed preparation in patients with wound gape.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2010/091/000542
Enrollment
60
Registered
2010-07-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Wound gape

Interventions

Intervention1: wound dressing: 200gms of raw papaya grated and placed between layers of a sterile gauze used for dressing which is placed between the edges of the gaped surgical wound. Control Interve

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Post caesarean section patients with wound gape which is defined as absence of continuity between edges of the surgical wound after removal of sutures on the seventh post-operative day. 2) All patients admitted during the study period willing to participate in the study by giving an informed consent.

Exclusion criteria

Exclusion criteria: 1) Severe systemic illnesses like diabetes, hypothyroidism which impair wound healing 2) Immunodeficiency states including HIV infection and steroid therapy. 3) Complete burst abdomen involving separation of peritoneum and rectus with evisceration. 4) Severe anaemia with haemoglobin concentration below 6gm%. 5) History of allergy to any of the study medications. 6) Body mass index greater than 30.

Design outcomes

Primary

MeasureTime frame
End point in both groups is healthy granulation tissue defined as pink tissue with beaded or granular appearance with serous non ?foul smelling discharge and absence of slough. Dressing in both groups is continued as long as end point is achieved and once the end point is achieved, the patient is posted for re-suturing.Timepoint: Number of days for which dressing was required before achieving the end point will be noted. Patient will be followed up until surgical wound healing is adequately achieved.

Secondary

MeasureTime frame
Safety and tolerability of study medications is accessed by questioning the patient regarding any adverse effect that the patient recalls.Timepoint: Patients are closely monitored daily for any adverse effects or hypersensitivity reactions.

Countries

India

Contacts

Public ContactDr.Mangala Bhaskar Murthy

Dr.M.B.Murthy,Assistant professor, Department of pharmacology, Government medical college, Miraj.Pandharpur road, Miraj.

mangala.bhaskar@gmail.com0233-2232090

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026