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A clinical trial to study the effect of two intravenous fluids,starch and dextran on blood sugar levels during surgery.

Effect of 6% Hydroxyethyl starch-450 and Low molecular weight Dextran on blood sugar levels during surgery under subarachnoid block - A prospective randomized study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2010/091/000340
Enrollment
180
Registered
2010-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 6% Hydroxyethyl starch-450,Dextran-40: preloading dose 10ml/kg Control Intervention1: Ringer&#039
s lactate solution: preloading dose 20ml/kg

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1, nondiabetic patients, 20 to 60 years of age, weighing 40 to 70 kg, undergoing elective lower limb or lower abdominal surgical procedures ,which were anticipated to complete within 2 hours,

Exclusion criteria

Exclusion criteria: Patients on regular use of steroids and ascorbic acid, Diabetic patients,Similarly, patients with a low haematocrit (PCV<30%), procedures prolonged due to anaesthetic or surgical complications ,or cases requiring blood transfusion due to more than predicted intraoperative blood loss and Patients developing an allergic reaction to the study fluids were excluded from the study.

Design outcomes

Primary

MeasureTime frame
Raised capillary blood glucose levels with all fluids.Timepoint: upto 3 hours post surgery.

Secondary

MeasureTime frame
Dextran-40 raises the blood sugar level, which goes well above physiological limits.Timepoint: upto 4 hours post surgery.

Countries

India

Contacts

Public ContactDr.Abhiruchi Patki
abhiruchipatki2204@yahoo.co.in0712-9890451964

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026