Health Condition 1: null- Infectious Gastroenteritis
Conditions
Interventions
Intervention1: Lactobacillus GG: 10 billion organisms given mixed in milk as food supplement once daily for four weeks
Control Intervention1: Inulin:
Sponsors
Christian Medical College Vellore
Eligibility
Inclusion criteria
Inclusion criteria: Male and female children aged 6 months to 5 years Diagnosis of rotaviral or cryptosporidial gastroenteritis (Rotavirus or Cryptosporidium EIA positive and three or more watery stools within a 24-hour period) No other enteric pathogen isolated from the stool at the time of enrollment ?Able to take the contents of study capsules mixed into food or milk ?No need for antibiotics for current illness No use of LGG/other probiotics within 30 days (yogurt consumption is not an exclusion criterion) HIV negative No severe malnutrition (WAZ score < 3SD below the median) No evidence of active bowel leak, acute abdomen or colitis No history of allergy Parent/guardian willing to report on compliance and side effects during the study period Families willing to provide informed consent, participate in study and have study personnel visit their home.
Exclusion criteria
Exclusion criteria: Other enteric pathogens isolated from the stool at the time of enrollment Not willing or able to take the contents of study capsules mixed into food or milk Need for antibiotics for current illness HIV positive Severe malnutrition (WAZ score Presence of active bowel leak, acute abdomen or colitis ?History of allergy Parent/guardian not willing to report on compliance and side effects during the study period Families not willing to provide informed consent, participate in study or have study personnel visit their home.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IgG to rotavirus VP6 or cryptosporidial g15 at 4 weeksTimepoint: 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Lactulose:mannitol test at 4 weeksTimepoint: 4 weeks | — |
Countries
India
Contacts
Public ContactGagandeep Kang
Outcome results
None listed