None listed
Conditions
Interventions
Intervention1: Ethinyl oestradiol with desogestrel: 1 tablet daily from day 1 of period for 21 days then 7 days gap and again for 21 days and so on cyclically for 6 months.
Control Intervention1: Ethi
Sponsors
DR.SUDHINDRA MOHAN BHATTACHARYA
Eligibility
Inclusion criteria
Inclusion criteria: women with oligomenorrhoea diagnosed as having Polycystic ovary syndrome as per the Rotterdam criteria 2003 ; age - from minimum gynaecological age of 3 years (age since menarche) to 35 years .
Exclusion criteria
Exclusion criteria: secondary causes of hyperandrogenism like gross hypothyroidism, hyperprolactinaemia, Cushing syndrome, late onset congenital adrenal hyperplasia; contraindications of oral pill therapy; severe liver disease, renal disease, cardiac disease; those who had already taken oral pills in the preceding 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| primary outcome- changes in clinical markers like BMI, Abdominal circumference, hirsutism score, acne, acanthosis nigricans.and biochemical markers like serum testosterone levels, SHBG levels and free androgen index; fasting sugar and fasting insulin levels and glucose: insulin ratio.Timepoint: baseline at the beginning of treatment. finally after 6 months of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| secondary out come- any side effects notedTimepoint: 6 months after treatment completion. | — |
Countries
India
Contacts
Public ContactDR.SUDHINDRA MOHAN BHATTACHARYA
Outcome results
None listed