A clinical trial to study the effects of seven sequences of Pranayama and oral hypoglycemic drugs versus only oral hypoglycemic drugs in type 2 diabetes mellitus.

An Open Label, Balanced, Randomized, Controlled, Parallel Design Microarray based Gene Expression Profiling Study to Evaluate the molecular mechanisms regulated in Type 2 Diabetes patients subjected to the seven sequences of Pranayama and oral hypoglycemic drugs versus only oral hypoglycemic drugs. Acronym PRAN

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2010/091/000188

Enrollment

Registered

2010-04-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Seven Sequences of Pranayama and Oral hypoglycemic drug: Nil Control Intervention1: Oral Hypoglycemic Drugs: Nil

Eligibility

Inclusion criteria

Inclusion criteria: Patient with Established type 2 diabetes (duration 1-10 years), on oral hypoglycemic agents (like Metformin or Glibenclamide) willing to participate in the study; Between 18-60 years.

Exclusion criteria

Exclusion criteria: Patient on insulin or patients with diabetic complications like neuropathy, retinopathy, nephropathy, diabetic foot, chronic ulcer and cardiovascular diseases

Design outcomes

Primary

Measure	Time frame
Fold expression level of genes related to endocrine, metabolism, Insulin signalling and regulation. Specific genes involved in the enzymatic degradation of insulin including PplGl.3, TC69229, UPlQ93YG9 and PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 SLC30A8 and other associated gene involved in the progression and onset of type 2 diabetes. Timepoint:	—

Secondary

Measure	Time frame
Significant changes in the Expression level Insulin-degrading enzyme. Significant effect of practicing Pranayama for the management of type 2 diabetes mellitus. AEs observed and reported by the patient, after practicing seven sequence of Pranayama.Timepoint:	—

Countries

India

Contacts

Public ContactDr. Rajesh Ranjan

dr.ranjan@aurigaresearch.com011-45754546

Outcome results