FindTrial
Sign In

A clinical trial to study the prediction of result of chemotherapy in Acute myeloid leukemia by evaluating in vitro DNA damage.

In vitro DNA damage assessment as predictor of response to chemotherapy in acute myeloid leukemia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2010/091/000015
Enrollment
30
Registered
2010-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: It is an observational study, no intervention will be done: Control Intervention1: It is an observational study, no intervention will be done:

Sponsors

Dr. KH Reeta, Assistant professor Department of Pharmacology AIIMS, New Delhi-110029
Lead Sponsor
Department of Pharmacology, AIIMS, New Delhi
Collaborator
PROF YK GUPTA
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients of acute myeloid leukemia of either sex in the age ≤ 60 years who are willing for treatment.

Exclusion criteria

Exclusion criteria: (1) Patients with aleukemic leukemia. (2) Patients with AML M3 sub type. (3) Patients with contraindication for chemotherapy. (4) Patients not willing for the treatment. (5) Patients not giving written consent for the study.

Design outcomes

Primary

MeasureTime frame
Correlation between the results of in vitro study and outcome of induction chemotherapy in terms of complete remission achieved or not.Timepoint: Baseline and at 21-28 days after induction chemotherapy—

Secondary

MeasureTime frame
To see if there is any difference in the study results from bone marrow samples and peripheral blood samples.Timepoint: 21-28 days after induction chemotherapy—

Countries

India

Contacts

Public ContactDR HEMANT SINGH BHADAURIA

All India Institute of Medical Sciences

drsinghhemant@gmail.com09990866131

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026