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A clinical trial to compare ringer lactate and nornal saline for rapid intravenous hydration in children with acute diarrhoea

Comparison of Ringer lactate and Normal saline for rapid intravenous rehydration in children with acute diarrhea- a randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2009/091/001084
Enrollment
22
Registered
2010-01-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ringer Lactate: Intervention2: Ringer&#039
s Lactate: The treatment will be given according to WHO guide lines. Children less than 1 year and 1-5 years of age will receive first 30 ml/kg over 1 hour and &frac12
hours respectively. Remaining 70 ml/kg will be given over 5 hours and 2&frac12
hours respectively. Control Intervention1: Normal Saline: Control Intervention2: Normal Saline: The treatment will be given according to WHO guide lines. Children less than 1 year and 1-5 years of ag
hours respectively.

Sponsors

Dr Vidushi Mahajan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All children with acute diarrhea

Exclusion criteria

Exclusion criteria: A) Persistent or chronic diarrhoea (>14 days). B) Known systemic disease (cardiac, endocrine, neurologic, chronic renal failure) C) Lethal malformations, D) Hypoglycaemia (glucose <40 mg/dL) done by dextrostix at the time of presentation.

Design outcomes

Primary

MeasureTime frame
pH at normalization of vital parameters (HR, RR, BP, CFT, and pulse volume) along with resolution of signs of severe dehydrationTimepoint: at normalization of vital parameters (HR, RR, BP, CFT, and pulse volume) along with resolution of signs of severe dehydration

Secondary

MeasureTime frame
1. All cause mortality during hospital stay. 2. Duration of hospital stay. 3. Change in blood Na, K, Cl after completion of rapid correction. 4. Amount of intravenous fluid and time required for rehydration. 5. Thrombotic events during hospital stay. 6. Local complications at the site of intravenous cannulation during intravenous hydration. Timepoint: At discharge

Countries

India

Contacts

Public ContactVidushi Mahajan
vidushimahajan2003@yahoo.co.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026